Enniatin B
Overview | |
Catalog # | bs-70512c-1-mg |
Product Name | Enniatin B |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
Target | |
Product Information | CAS Number: 917-13-5 Molecular formula: C33H57N3O9 Molecular weight: 639.8 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO, ethanol, methanol or DMF. Almost insoluble in water. InChiKey: MIZMDSVSLSIMSC-VYLWARHZSA-N SMILES: CC(C)[C@H]1OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C1=O)C(C)C)C(C)C |
Description | Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic (less ionophoric than Enniatin A). Incorporation into the cell membrane forms dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. Anticancer compound. Triggers apoptosis in several cancer cell lines. Moderate inhibitor of ACAT (acylcoenzyme A:cholesterolacyl transferase). Inhibitor of the pleiotropic drug resistance protein 5 (Pdr5p) in yeast. Shown to have a variety of other biological activities such as antifungal, anthelmintic, insecticidal, immunomodulatory and phytotoxic activity. |