Overview |
bsm-52012R |
Alas1 (1G11) Monoclonal Antibody |
WB, IF(ICC) |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
Recombinant human Alas1 protein, around C-terminal 200aa. |
Monoclonal |
1G11 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
211 |
P13196 |
5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS1; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1; ALAS1; ALAS3; ALASH; OK/SW-cl.121 |
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015] |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |