HSD11B2 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Mouse
  • Rat
  • Horse

Predicted Reactivity

  • Human
  • Dog
Overview
Catalog # bs-3618R-Biotin
Product Name HSD11B2 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Mouse, Rat, Horse
Predicted Reactivity Human, Dog
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HSD11B2
Immunogen Range 151-250/405
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3291
Swiss Prot P80365
Subcellular location Cytoplasm
Synonyms Corticosteroid 11-beta-dehydrogenase isozyme 2; 11-beta-hydroxysteroid dehydrogenase type 2; 11-DH2; 11-beta-HSD2; 11-beta-hydroxysteroid dehydrogenase type II; -HSD11 type II; NAD-dependent 11-beta-hydroxysteroid dehydrogenase; 11-beta-HSD; HSD11B2; HSD11K
Background Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500