PPAR Gamma (ser273) Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
  • Sheep
  • Guinea Pig

Predicted Reactivity

  • Cow
  • Chicken
  • Rabbit
Overview
Catalog # bs-4888R-A680
Product Name PPAR Gamma (ser273) Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human, Mouse, Rat, Sheep, Guinea Pig
Predicted Reactivity Cow, Chicken, Rabbit
Specifications
Conjugation ALEXA FLUOR® 680
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human PPAR Gamma around the phosphorylation site of ser273
Modification Site ser273
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5468
Swiss Prot P37231
Subcellular location Cytoplasm, Nucleus
Synonyms GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG
Background Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200