Recombinant SARS-CoV-2 Nucleocapsid protein

OVERVIEW
CATALOG # bs41408P
PRODUCT NAME Recombinant SARS-CoV-2 Nucleocapsid protein
CROSS REACTIVE SPECIES DETAILS Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
CONJUGATION Unconjugated
SOURCE An E.coli expression system produces recombinant SARS-CoV-2 Nucleocapsid protein, and the target gene encoding Met1-Ala419 is expressed with N-His Tag
EXPRESSION SYSTEM E.coli
TAG N-His Tag
PREDICTED MOLECULAR MASS 47.79kDa
PURITY >95% as determined by SDS-PAGE
FORMULATION Lyophilized from 0.22um filtered solution in PBS (pH 7.4). 5 % trehalose is added as a protectant before lyophilization.
STORAGE Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt. Avoid repeated freeze/thaw cycles.
ENDOTOXIN LEVEL N/A
ACTIVITY ASSAY N/A
TARGET
ACCESSION # QHD43423.2
SYNONYMS Nucleoprotein
BACKGROUND The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an essential role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. The N protein of coronavirus is chosen as a diagnostic tool because of the conservation of the N protein sequence and its strong immunogenicity.
NOTE For research use only. Not for use in clinical diagnostic procedures.