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    Cytochrome C Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated

    Overview
    Catalog # bs-0013R-A350
    Product Name Cytochrome C Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
    Applications FCM, IF(IHC-P), IF(ICC)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation ALEXA FLUOR® 350
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human Cytochrome C
    Immunogen Range 50-89/105
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 54205
    Swiss Prot P99999
    Subcellular location Mitochondrion
    Synonyms CYC; HCS; THC4; Cytochrome c; CYCS
    Background Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.