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IDE Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Cow
  • Pig
  • Chicken
Overview
Catalog # bs-0018R-A594
Product Name IDE Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human, Mouse, Rat
Predicted Reactivity Cow, Pig, Chicken
Specifications
Conjugation ALEXA FLUOR® 594
Host Rabbit
Source KLH conjugated synthetic peptide derived from human IDE
Immunogen Range 491-590/1019
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 3416
Swiss Prot P14735
Subcellular location Cytoplasm, Secreted, Cell membrane
Synonyms INSULYSIN; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; IDE
Background Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200