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    APAF1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated

    Description:
    Applications:
    • IF(IHC-P)
    Overview
    Catalog # bs-0059R-A647
    Product Name APAF1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation ALEXA FLUOR® 647
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human Apaf-1
    Immunogen Range 3-44/1248
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 317
    Swiss Prot O14727
    Subcellular location Cytoplasm
    Synonyms CED4; APAF-1; Apoptotic protease-activating factor 1; APAF1; KIAA0413
    Background Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
    Applications
    Application Dilution
    IF(IHC-P) 1:50-200