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    Leptin receptor Polyclonal Antibody

    • FCM
    Catalog # bs-0109M
    Product Name Leptin receptor Polyclonal Antibody
    Applications FCM
    Reactivity Human, Rat
    Conjugation Unconjugated
    Host Mouse
    Source KLH conjugated synthetic peptide derived from human Leptin receptor
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
    Subcellular location Cytoplasm
    Synonyms obl; CD 295; CD295; CD295 antigen; Db; Fa; HuB219; LEP R; LEPR; LEPROT; Leptin receptor fatty; Leptin receptor gene related protein; Leptin receptor precursor; OB R; OB R gene related protein; OB receptor; OB-RGRP; Obr.
    Background Leptin receptor (OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. An OB-R transcript encodes a soluble form of the receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist. Human OB-R encodes a 1 165 amino acid residue precursor protein with a 22 amino acid residue signal peptide, an 816 amino acid residue extracellular domain, a 21 amino acid residue transmembrane domain and a 303 amino acid residue cytoplasmic domain.
    Application Dilution
    FCM 1:20-100