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    APP/Amyloid Precursor Protein Antibody, ALEXA FLUOR® 350 Conjugated

    Description:
    Applications:
    • IF(IHC-P)
    Overview
    Catalog # bs-0112R-A350
    Product Name APP/Amyloid Precursor Protein Antibody, ALEXA FLUOR® 350 Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation ALEXA FLUOR® 350
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human of human APP
    Immunogen Range 380-430/770
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 351
    Swiss Prot P05067
    Subcellular location Extracellular
    Synonyms AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; Amyloid beta A4 protein; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; PreA4; Protease nexin-II; A4
    Background This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
    Applications
    Application Dilution
    IF(IHC-P) 1:50-200