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    CD45 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated

    Description:
    Applications:
    • FCM
    • IF(IHC-P)
    Overview
    Catalog # bs-0522R-A350
    Product Name CD45 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
    Applications FCM, IF(IHC-P)
    Reactivity Human
    Specifications
    Conjugation ALEXA FLUOR® 350
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human CD45
    Immunogen Range 1210-1260/1304
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 5788
    Swiss Prot P08575
    Synonyms LCA; LY5; B22; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC
    Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
    Applications
    Application Dilution
    FCM 1:20-100
    IF(IHC-P) 1:50-200