CD45 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated

Applications

  • FCM
  • IF(IHC-P)

Reactivity

  • Human
Overview
Catalog # bs-0522R-A488
Product Name CD45 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications FCM, IF(IHC-P)
Specificity The antibody is predicted to work with Mouse and Rat samples, but with decreased sensitivity compared to human samples.
Reactivity Human
Specifications
Conjugation ALEXA FLUOR® 488
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CD45
Immunogen Range 1210-1260/1306
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target
Gene ID 5788
Swiss Prot P08575
Synonyms LCA; LY5; B220; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC
Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Application Dilution
FCM 1:20-100
IF(IHC-P) 1:50-200