CD45 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated

Applications

  • FCM
  • IF(IHC-P)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
  • Rabbit

Predicted Reactivity

  • Cow
Overview
Catalog # bs-0522R-A594
Product Name CD45 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Applications FCM, IF(IHC-P), IF(ICC)
Specificity The antibody is predicted to work with Mouse and Rat samples, but with decreased sensitivity compared to human samples.
Reactivity Human, Mouse, Rat, Rabbit
Predicted Reactivity Cow
Specifications
Conjugation ALEXA FLUOR® 594
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CD45
Immunogen Range 1210-1304/1304
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition Store at 4°C for 12 months.
Target
Gene ID 5788
Swiss Prot P08575
Subcellular location Cell membrane
Synonyms LCA; LY5; B220; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC
Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Application Dilution
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200