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    Connexin 43 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated

    Catalog # bs-0651R-A488
    Product Name Connexin 43 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
    Applications FCM, IF(IHC-P), IF(ICC)
    Reactivity Human, Mouse, Rat, Dog
    Conjugation ALEXA FLUOR® 488
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human Connexin-43
    Immunogen Range 232-282/282
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Gene ID 2697
    Swiss Prot P17302
    Subcellular location Cytoplasm
    Synonyms HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; Gap junction alpha-1 protein; Connexin-43; Gap junction 43 kDa heart protein; GJA1
    Background Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).