Overview |
bs-0818R-A488 |
MrpL28 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated |
IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse, Rat, Cow, Chicken |
Specifications |
ALEXA FLUOR® 488 |
Rabbit |
KLH conjugated synthetic peptide derived from human MrpL28 |
131-240/240 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
10573 |
Cytoplasm |
RM28_HUMAN; 39S ribosomal protein L28 mitochondrial; 39S ribosomal protein L28 mitochondrial precursor; HGNC6756; L28mt ; MAAT 1; MAAT1; Melanoma antigen p15; Melanoma associated antigen recognised by cytotoxic T lymphocytes; Melanoma associated antigen recognized by T lymphocytes; MGC8499; Mitochondrial ribosomal protein L28; MRP L28; MRPL 28; P15. |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL28 is a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA A24 restricted fashion. |
Application Dilution |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |