VCAM1 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat
  • Sheep
  • Rabbit

Predicted Reactivity

  • Pig
Overview
Catalog # bs-0920R-Biotin
Product Name VCAM1 Polyclonal Antibody, Biotin Conjugated
Applications WB, IHC-P, IHC-F
Reactivity Human, Mouse, Rat, Sheep, Rabbit
Predicted Reactivity Pig
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human VCAM-1
Immunogen Range 651-739/739
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 7412
Swiss Prot P19320
Subcellular location Cell membrane
Synonyms CD106; INCAM-1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; VCAM1; L1CAM
Background Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500