HHV DNA polymerase catalytic subunit Antibody

Applications

  • IHC-P
  • IF(IHC-P)

Reactivity

  • Virus
Overview
Catalog # bs-10489R
Product Name HHV DNA polymerase catalytic subunit Antibody
Applications IHC-P, IF(IHC-P)
Specificity This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit
Reactivity Virus
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit
Immunogen Range 1200-1235/1235
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Synonyms DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046.
Background Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.
Application Dilution
IHC-P 1:200-400
IF(IHC-P) 1:50-200