CD101 Polyclonal Antibody

Applications

  • WB
  • IHC-P

Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-10727R
Product Name CD101 Polyclonal Antibody
Applications WB, IHC-P
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CD101
Immunogen Range 95-130/1021
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 9398
Swiss Prot Q93033
Subcellular location Extracellular
Synonyms V7; IGSF2; EWI-101; Immunoglobulin superfamily member 2; Cell surface glycoprotein V7; Glu-Trp-Ile EWI motif-containing protein 101; CD101; EWI101
Background Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Application Dilution
WB 1:300-1000
IHC-P 1:200-400