Tetanus Toxin heavy chain Antibody

Applications

  • IHC-P
  • IF(IHC-P)

Reactivity

  • Bacteria
Overview
Catalog # bs-11772R
Product Name Tetanus Toxin heavy chain Antibody
Applications IHC-P, IF(IHC-P)
Reactivity Bacteria
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin heavy chain
Immunogen Range 820-870/1315
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 24255210
Swiss Prot P04958
Synonyms Tetanus toxin; Tentoxylysin; tetX; CTC_p60
Background Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
Application Dilution
IHC-P 1:200-400
IF(IHC-P) 1:50-200