Overview |
bs-1192R-PE |
CD14 Polyclonal Antibody, PE Conjugated |
WB |
Human, Mouse, Rat, Dog, Sheep, Rabbit |
Cow, Pig |
Specifications |
PE |
Rabbit |
KLH conjugated synthetic peptide derived from mouse CD14 |
201-300/366 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
12475 |
P10810 |
Cell membrane |
Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14 |
In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity). |
Application Dilution |
WB |
1:300-5000 |