CD14 Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Sheep
  • Rabbit

Predicted Reactivity

  • Cow
  • Pig
Overview
Catalog # bs-1192R-PE
Product Name CD14 Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Human, Mouse, Rat, Dog, Sheep, Rabbit
Predicted Reactivity Cow, Pig
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse CD14
Immunogen Range 201-300/366
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 12475
Swiss Prot P10810
Subcellular location Cell membrane
Synonyms Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14
Background In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).
Application Dilution
WB 1:300-5000