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    CD14 Polyclonal Antibody, Biotin Conjugated

    Overview
    Catalog # bs-1192R-Biotin
    Product Name CD14 Polyclonal Antibody, Biotin Conjugated
    Applications WB, IHC-P
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation Biotin
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from mouse CD14
    Immunogen Range 240-270/366
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
    Target
    Gene ID 12475
    Swiss Prot P10810
    Subcellular location Extracellular
    Synonyms Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14
    Background In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).