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    Pecanex Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated

    Overview
    Catalog # bs-11932R-A647
    Product Name Pecanex Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation ALEXA FLUOR® 647
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human Pecanex
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 22990
    Synonyms PCNXL1; Pecanex homolog; Pecanex like protein 1; PCX1_HUMAN.
    Background Human Pecanex proteins are homologs of the Drosophila Pecanex protein, a maternal-effect neurogenic protein that is involved in normal development of the fly nervous system. Three human Pecanex homologs exist, designated Pecanex, Pecanex 2, also known as PCNXL2 (pecanex-like 2), and Pecanex 3. Pecanex 2 is a 2,137 amino acid multi-pass membrane protein that exists as five alternatively spliced isoforms characterized by high mutational frequencies and biallelic mutations in colorectal tumors, thereby likely functioning as a target gene in these tumors. Pecanex 2 is encoded by a gene that maps to human chromosome 1q42.2, which is linked to an inherited microduplication. This microduplication that includes Pecanex 2 may play a role in autism and mild mental retardation.