ABCA1 (Ser2054) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Dog
  • Pig
Overview
Catalog # bs-12956R-A647
Product Name ABCA1 (Ser2054) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Mouse
Predicted Reactivity Human, Rat, Dog, Pig
Specifications
Conjugation ALEXA FLUOR® 647
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human ABCA1 around the phosphorylation site of Ser2054
Modification Site Ser2054
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 19
Subcellular location Cell membrane
Synonyms ABCA1 phospho S2054; p-ABCA1 phospho S2054; ATP binding cassette transporter A1; ABC 1; ABC Transporter 1; ABC1; ABCA 1; ABCA1; ATP binding Cassette 1; ATP binding cassette sub family A ABC1 member 1; ATP binding cassette sub family A member 1; ATP binding cassette sub-family A member 1; ATP binding Cassette Transporter 1; ATP-binding Cassette 1; ATP-binding Cassette Transporter 1; CERP; Cholesterol Efflux Regulatory Protein; FLJ14958; HDLDT1; Membrane bound; MGC164864; MGC165011; TD; TGD; ABCA1_HUMAN.
Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200