EXOC3L2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Cow
Overview
Catalog # bs-14660R-A350
Product Name EXOC3L2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Rat
Predicted Reactivity Human, Mouse, Cow
Specifications
Conjugation ALEXA FLUOR® 350
Host Rabbit
Source KLH conjugated synthetic peptide derived from human EXOC3L2
Immunogen Range 151-250/409
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 90332
Swiss Prot Q2M3D2
Subcellular location Cytoplasm, Nucleus
Synonyms Exocyst complex component 3 like; Exocyst complex component 3 like protein 2; FLJ36147; EX3L2_HUMAN; HBV X transactivated gene 7 protein; HBV XAg transactivated protein 7; MGC16332; OTTHUMP00000207128; OTTMUSP00000045827; Protein 7 transactivated by hepatitis B virus X antigen (HBxAg); XTP7.
Background Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. ExoC3L2 (Exocyst complex component 3-like protein 2), also known as HBV X-transactivated gene 7 protein, is a 409 amino acid protein that is related to the Sec6 component of the exocyst complex.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200