Gremlin 1 Polyclonal Antibody, Biotin Conjugated

Applications

  • IHC-P

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-1475R-Biotin
Product Name Gremlin 1 Polyclonal Antibody, Biotin Conjugated
Applications IHC-P
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human gremlin 1
Immunogen Range 130-170/184
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 26585
Swiss Prot O60565
Subcellular location Secreted
Synonyms DRM; HMPS; PIG2; CRAC1; DAND2; IHG-2; GREMLIN; CKTSF1B1; Gremlin-1; Cell proliferation-inducing gene 2 protein; Cysteine knot superfamily 1, BMP antagonist 1; DAN domain family member 2; Down-regulated in Mos-transformed cells protein; Increased in high glucose protein 2; GREM1
Background Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis (By similarity).
Application Dilution
IHC-P 1:200-400