SSEA3 Polyclonal Antibody

Applications

  • IHC-P
  • IF(IHC-P)
  • IF(ICC)

Reactivity

  • Human
  • Rat
Overview
Catalog # bs-3575R
Product Name SSEA3 Polyclonal Antibody
Applications IHC-P, IF(IHC-P), IF(ICC)
Reactivity Human, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source 4-8 cell stage mouse embryos
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Subcellular location Cell membrane
Synonyms SSEA-3; Stage specic embryonic antigen 3; Stage specic embryonic antigen 3.
Background SSEA3 is a globoseries carbohydrate antigen present on both cell surface glycolipids and glycopeptides. It is found on the surface of mouse oocytes, becoming restricted to the intracellular mass of the early blastocyst and then to the primitive endoderm. It is present on the surface of human teratocarcinoma cells (EC), embryonic germ cells (EG) and embryonic stem cells (ES) but not mouse undifferentiated mouse cells of these types. SSEA3 expression decreases as human EC, ES and EG cells differentiate but increases on differentiation of mouse EC, ES and EG cells. It is also found on the surface of mouse erythrocytes.
Application Dilution
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200