Overview |
bs-4820R |
CD45 Polyclonal Antibody |
ELISA, FCM, IHC-P |
Human |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human CD45/B220 |
401-500/1304 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
Store at -20°C for 12 months.. |
Target |
5788 |
P08575 |
Cell membrane |
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC |
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). |
Application Dilution |
ELISA |
1:500-1000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |