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SB 202190

Overview
Catalog # bs-83631c-10-mg
Product Name SB 202190
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information Potent and selective p38 MAP kinase inhibitor acting at the ATP site1. Selectively inhibits the p38α and β isoforms (IC50= 50 and 100 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively)2. Effectively blocks LPS-induced gene expression in monocytes3. Induces apoptosis4. Cell permeable.
Description CAS Number: 152121-30-7

Chemical Name: 4-[4-(4-Fluorophenyl)-5-(4-pyridiny¬l)-1H-imidazol-2-yl]phenol

Molecular Weight: 331.35

Formula: C20H14N3OF

Solubility: DMSO (30 mg/ml)

Physical Properties: Yellow solid

Purity: 98% by TLC [10% CH3OH in CH2Cl2, Rf = 0.25] NMR (Conforms)