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IP3 Receptor Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated

Applications

  • FCM

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-8869R-A350
Product Name IP3 Receptor Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
Applications FCM
Reactivity Human, Mouse, Rat
Specifications
Conjugation ALEXA FLUOR® 350
Host Rabbit
Source KLH conjugated synthetic peptide derived from human IP3 Receptor
Immunogen Range 101-200/2758
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 3708
Swiss Prot Q14643
Subcellular location Cytoplasm
Synonyms ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1
Background Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Application Dilution
FCM 1:200