Overview |
bsm-0991M |
HPV18 E6 protein (2F6) Monoclonal Antibody |
IHC-P, IF(IHC-P) |
Virus |
Specifications |
Unconjugated |
Mouse |
KLH conjugated synthetic peptide derived from HPV18 E6 protein |
105-141/158 |
Monoclonal |
2F6 |
IgG |
1ug/ul |
Purified by Protein G. |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
Store at -20°C for 12 months.. |
Target |
1489088 |
P06463 |
Protein E6; E6 |
Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation. |
Application Dilution |
IHC-P |
1:200-400 |
IF(IHC-P) |
1:50-200 |