| Overview |
| bsm-0991M |
| HPV18 E6 protein (2F6) Monoclonal Antibody |
| IHC-P, IF(IHC-P) |
| Virus |
| Specifications |
| Unconjugated |
| Mouse |
| KLH conjugated synthetic peptide derived from HPV18 E6 protein |
| 105-141/158 |
| Monoclonal |
| 2F6 |
| IgG |
| 1ug/ul |
| Purified by Protein G. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 1489088 |
| P06463 |
| Protein E6; E6 |
| Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation. |
| Application Dilution |
| IHC-P |
1:100-500 |
| IF(IHC-P) |
1:100-500 |