Overview |
bsm-0991M |
HPV18 E6 protein (2F6) Monoclonal Antibody |
IHC-P, IF(IHC-P) |
Virus |
Specifications |
Unconjugated |
Mouse |
KLH conjugated synthetic peptide derived from HPV18 E6 protein |
105-141/158 |
Monoclonal |
2F6 |
IgG |
1ug/ul |
Purified by Protein G. |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
Target |
1489088 |
P06463 |
Protein E6; E6 |
Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation. |
Application Dilution |
IHC-P |
1:100-500 |
IF(IHC-P) |
1:100-500 |