HPV18 E6 protein (2F6) Monoclonal Antibody

Applications

  • IHC-P
  • IF(IHC-P)

Reactivity

  • Virus
Overview
Catalog # bsm-0991M
Product Name HPV18 E6 protein (2F6) Monoclonal Antibody
Applications IHC-P, IF(IHC-P)
Reactivity Virus
Specifications
Conjugation Unconjugated
Host Mouse
Source KLH conjugated synthetic peptide derived from HPV18 E6 protein
Immunogen Range 105-141/158
Clonality Monoclonal
Clone # 2F6
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 1489088
Swiss Prot P06463
Synonyms Protein E6; E6
Background Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation.
Application Dilution
IHC-P 1:200-400
IF(IHC-P) 1:50-200