Fibronectin/FN1 Monoclonal Antibody, APC-Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-33143m-apc-cy7-100ul |
| Product Name | Fibronectin/FN1 Monoclonal Antibody, APC-Cy7 Conjugated |
| Applications | WB, IF(IHC-P) |
| Reactivity | Human |
| Specifications | |
| Conjugation | APC-Cy7 |
| Host | Mouse |
| Source | KLH conjugated synthetic peptide derived from human Fibronectin |
| Clonality | Monoclonal |
| Clone # | 1B9 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein G. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2335 |
| Swiss Prot | P02751 |
| Synonyms | Fibronectin; FN1; Cold-insoluble globulin; CIG |
| Background | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
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