Complement factor B (28A3) Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-50226M
Product Name Complement factor B (28A3) Monoclonal Antibody
Applications WB
Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Source Protein purified from Human plasma
Clonality Monoclonal
Clone # 28A3
Isotype IgG1 κ
Concentration 4ug/ul
Purification Purified by Protein G.
Storage HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Store for 1 year at -20°C from date of shipment.
Target
Gene ID 629
Swiss Prot P00751
Synonyms BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; Complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; Properdin factor B; CFB
Background Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Application Dilution
WB 1:300-1000