Overview |
bsm-50360M |
ILK (22F1) Monoclonal Antibody |
WB |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Mouse |
Recombinant human protein purified from E.coli (His-ILK) |
Monoclonal |
22F1 |
IgG1 |
1ug/ul |
Purified by Protein G. |
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment. |
Target |
3611 |
Q13418 |
P59; ILK-1; ILK-2; p59ILK; HEL-S-28; Integrin-linked protein kinase; 59 kDa serine/threonine-protein kinase; ILK; ILK1; ILK2 |
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. |
Application Dilution |
WB |
1:300-1000 |