4E-BP1 (3G1) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-52007R
Product Name 4E-BP1 (3G1) Monoclonal Antibody
Applications WB, IHC-P, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Mouse
Source Synthetic peptide derived from human 4E-BP1, around N-terminal.
Clonality Monoclonal
Clone # 3G1
Isotype IgG1
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. Store at -20°C for 12 months.
Target
Gene ID 1978
Swiss Prot Q13541
Synonyms e4EBP1; Eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; 4EBP1; BP 1; BP1; e4E binding protein 1; e4E-binding protein 1; Eukaryotic translation initiation factor 4E binding protein 1; MGC4316; PHAS I; PHASI; PHAS-I; PHAS; 4E-BP1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; Phosphorylated heat and acid stable protein regulated by insulin 1; 4EBP1_HUMAN.
Background This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
Application Dilution
WB 1:300-1000
IHC-P 1:200-400
IF