ARF6 (5H4) Monoclonal Antibody

Applications

  • WB
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-52017R
Product Name ARF6 (5H4) Monoclonal Antibody
Applications WB, IF(ICC)
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant human ARF6 protein, full length.
Clonality Monoclonal
Clone # 5H4
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. Store at -20°C for 12 months.
Target
Gene ID 382
Swiss Prot P62330
Synonyms ADP-ribosylation factor 6; ARF6
Background GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.
Application Dilution
WB 1:1000-2000
IF(ICC) 1:100-1:500