p95/NBS1(S343) (5B5) Monoclonal Antibody

Applications

  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-52184R
Product Name p95/NBS1(S343) (5B5) Monoclonal Antibody
Applications IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic peptide derived from human p95/NBS1(S343), around 350-400aa (phospho S343).
Modification Site S343
Clonality Monoclonal
Clone # 5B5
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. Store at -20°C for 12 months.
Target
Gene ID 4683
Swiss Prot O60934
Synonyms neuronal thread protein AD7c-NTP; AD7c-NTP.
Background This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease.
Application Dilution
IF(ICC) 1:50-200