LRP1 (1F4) Monoclonal Antibody

Applications

  • WB
  • FCM
  • IF(ICC)
  • IHC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-52239R
Product Name LRP1 (1F4) Monoclonal Antibody
Applications WB, FCM, IF(ICC), IHC
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Human LRP1 aa 4450 to the C-terminus
Clonality Monoclonal
Clone # 1F4
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. Store at -20°C for 12 months.
Target
Gene ID 4035
Swiss Prot Q07954
Synonyms Prolow-density lipoprotein receptor-related protein 1, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, CD_antigen: CD91, LRP-1, A2MR, APOER, CD91
Background Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
Application Dilution
WB 1:300-1000
FCM 1:20-100
IF(ICC) 1:50-200
IHC