MAD3 Monoclonal Antibody

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54664R
Product Name MAD3 Monoclonal Antibody
Applications WB, FCM
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic Peptide within N-terminal human MAD3.
Clonality Monoclonal
Clone # 11D8
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 83463
Swiss Prot Q9BW11
Subcellular location Nucleus
Synonyms bHLHc13 antibody, Class C basic helix-loop-helix protein 13 antibody, FLJ35523 antibody, Likely ortholog of mouse Max dimerization protein 3 antibody, MAD3_HUMAN antibody, MAX dimerization protein 3 antibody, Max dimerizer 3 antibody, Max-associated protein 3 antibody, Max-interacting transcriptional repressor MAD3 antibody, MGC2383 antibody, mxd3 antibody, Myx antibody, OTTHUMP00000223596 antibody, OTTHUMP00000223598 antibody
Background This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
Application Dilution
WB 1:300-5000
FCM 1:20-100