HLA F Monoclonal Antibody

Applications

  • WB
  • IHC-P

Reactivity

  • Human
Overview
Catalog # bsm-54713R
Product Name HLA F Monoclonal Antibody
Applications WB, IHC-P
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic Peptide corresponding to C terminal human HLA F.
Clonality Monoclonal
Clone # 4H
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3134
Swiss Prot P30511
Subcellular location Cell membrane, Lysosome membrane, Early endosome membrane
Synonyms CDA12 antibody, HLA 5.4 antibody, HLA class I histocompatibility antigen, alpha chain F antibody, HLA class I molecule antibody, HLA F antigen antibody, HLA-CDA12 antibody, HLA-F antibody, HLAF antibody, HLAF_HUMAN antibody, Leukocyte antigen F antibody, MHC class I antigen F antibody
Background This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
Application Dilution
WB 1:300-5000
IHC-P 1:200-400