{"product_id":"ihc0202h","title":"Human CRIM1 Ready-To-Use IHC Kit","description":"\u003ch1 data-mce-fragment=\"1\" style=\"text-align: center;\" data-mce-style=\"text-align: center;\"\u003e\n\u003cb data-mce-fragment=\"1\"\u003eHuman CRIM1 Ready-To-Use IHC Kit\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003e \u003c\/b\u003e\n\u003c\/h1\u003e\n\u003cb data-mce-fragment=\"1\"\u003eCat. No.: \u003c\/b\u003eIHC0202H\u003cb data-mce-fragment=\"1\"\u003e\u003cbr\u003eSample Type: \u003c\/b\u003eFFPE tissue \u003cb data-mce-fragment=\"1\"\u003e\u003cbr\u003eSize: \u003c\/b\u003e50T (including a control slide) \u003cb data-mce-fragment=\"1\"\u003e\u003cbr\u003eStorage and Stability: \u003c\/b\u003ePlease store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.\n\u003ch3\u003e\u003cb data-mce-fragment=\"1\"\u003eBackground\u003cbr\u003e\u003c\/b\u003e\u003c\/h3\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eCRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003ch3\u003e\u003cb data-mce-fragment=\"1\"\u003eSynonyms\u003c\/b\u003e\u003c\/h3\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eCysteine-rich motor neuron 1 protein, CRIM-1, Cysteine-rich repeat-containing protein S52, Processed cysteine-rich motor neuron 1protein, CRIM 1, CRIM1, Cysteine rich motor neuron 1 protein, Cysteine rich repeat containing protein S52, Cysteine rich transmembrane BMP regulator 1 (chordin like), Cysteine rich transmembrane BMP regulator 1, MGC138194, Processed cysteine rich motor neuron 1 protein, S52.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003ch3\u003e\u003cb data-mce-fragment=\"1\"\u003eMaterials Supplied\u003c\/b\u003e\u003c\/h3\u003e\n\u003ctable style=\"width: 100.791%;\"\u003e\n\u003cthead data-mce-fragment=\"1\"\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 7%;\"\u003eNumber\u003c\/th\u003e\n\u003cth style=\"width: 42%;\"\u003eComponent\u003c\/th\u003e\n\u003cth style=\"width: 12%;\"\u003e50T\u003c\/th\u003e\n\u003cth style=\"width: 20%;\"\u003eConcentration\u003c\/th\u003e\n\u003cth style=\"width: 12%;\"\u003eStorage\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e1\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003ePBS Buffer (powder)\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e2L x 2\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e20x\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003eRT\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e2\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eAntigen Retrieval Buffer\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e20ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e100x\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e2-8°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e3\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eEndogenous Peroxidase Blocking Buffer\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e3ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003eRTU\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003e2-8°C\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e4\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eBlocking Buffer\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e3ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003e2-8°C\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e5\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003ePrimary Antibody (Human CRIM1 Rabbit pAb)\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e6ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003e2-8°C\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e6\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eSecondary Antibody (Goat Anti-Rabbit IgG H\u0026amp;L \/ HRP)\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e6ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003e2-8°C\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e7\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eChromogen Component A\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e0.3ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e-20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e8\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eChromogen Component B\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e0.3ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003e-20°C\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e9\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eCounter Staining Reagent\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e5ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003eRT\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e10 \u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eDifferentiation Reagent\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e6ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003eRT\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 10%;\"\u003e11\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eMounting Media\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e5ml\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003eRT\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 7%;\"\u003e12\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eControl slide (Human placenta)\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e1 slide\u003c\/td\u003e\n\u003ctd style=\"width: 10%; text-align: center;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003eRTU\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003eRT\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 7%;\"\u003e13\u003c\/td\u003e\n\u003ctd style=\"width: 43%;\"\u003eDatasheet\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e1 copy\u003c\/td\u003e\n\u003ctd style=\"width: 10%;\"\u003e\u003cbr\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 14%;\"\u003e\u003cbr\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\u003cb data-mce-fragment=\"1\"\u003eNotes\u003cbr\u003e\u003c\/b\u003e\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\u003cb data-mce-fragment=\"1\"\u003eThe positive control slide provided in the kit allows you to be sure that the experimental set-up is working properly. \u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb data-mce-fragment=\"1\"\u003eDo not allow slides to dry at any time during this procedure. \u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb data-mce-fragment=\"1\"\u003ePlease don't replace the matching reagents in this product with other manufacturers' products. \u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb data-mce-fragment=\"1\"\u003eAs DAB is a carcinogen, please take necessary precautions. \u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb data-mce-fragment=\"1\"\u003ePBS (reagent 1) can be stored for one week at 4℃ after preparation; The antigen retrieval buffer (1×reagent 2) and the chromogenic agent (the mixture of reagents 7 and 8) should be prepared right before each assay.\u003c\/b\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\n\u003cbr\u003eAs DAB is a carcinogen, please take necessary precautions.\n\u003cbr\u003e\u003cbr\u003eImportant Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.\u003c\/p\u003e","brand":"Bioss","offers":[{"title":"50 Test","offer_id":49140890403115,"sku":"IHC0202H-Kit","price":499.0,"currency_code":"USD","in_stock":true},{"title":"Ab only","offer_id":50001294360875,"sku":"IHC0202H-Ab","price":350.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1223\/3460\/files\/IHC0202H_1_8d149afc-75c8-4c06-aad6-664d7578e1fa.png?v=1718209452","url":"https:\/\/www.biossusa.com\/products\/ihc0202h","provider":"Bioss","version":"1.0","type":"link"}