| Overview |
| bs-0598R-PE |
| DVL1 Polyclonal Antibody, PE Conjugated |
| WB, FCM |
| Human, Mouse, Rat |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human DVL1 |
| 21-100/695 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1855 |
| O14640 |
| Cytoplasm, Cell membrane |
| DVL; DVL1L1; DVL1P1; Segment polarity protein dishevelled homolog DVL-1; Dishevelled-1; DSH homolog 1; DVL1 |
| Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ). |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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