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CD32B(Tyr292) Polyclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse
  • Monkey

Predicted Reactivity

  • Rat
  • Dog
  • Sheep
  • Pig
  • Rabbit
  • Guinea Pig
Overview
Catalog # bs-6031R-PE-Cy5
Product Name CD32B(Tyr292) Polyclonal Antibody, PE-Cy5 Conjugated
Applications WB, FCM
Reactivity Human, Mouse, Monkey
Predicted Reactivity Rat, Dog, Sheep, Pig, Rabbit, Guinea Pig
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human CD32B around the phosphorylation site of Tyr292.
Modification Site Tyr292
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2213
Swiss Prot P31994
Subcellular location Cell membrane
Synonyms CD32; FCG2; CD32B; FCGR2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; FCGR2B
Background Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Application Dilution
WB 1:300-5000
FCM 1:20-100