Rapamycin

Overview
Catalog #	bs-83151c-50mg
Product Name	Rapamycin
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Clinically useful immunosuppressant. Inhibits the response to interleukin-2 blocking activation of T- and B-cells.1 Rapamycin forms a complex with cytosolic FK-binding protein 12 (FKB12) that binds to mTOR Complex1(mTORC1) inhibiting the mammalian target of rapamycin (mTOR).2 Also binds to mTORC2 leading to decreased glucose tolerance and insensitivity to insulin.3 Induces autophagy.4
Description	CAS Number: 53123-88-9 Chemical Name: mTOR inhibitor Molecular Weight: 914.17 Formula: C51H79NO13 Solubility: DMSO (40 mg/ml) Ethanol (90 mg/ml) Physical Properties: White solid Purity: 98% NMR Conforms