| Overview |
| bs-3651R-FITC |
| F11R/JAM-A/CD321 Polyclonal Antibody, FITC Conjugated |
| WB |
| Human |
| Mouse, Rat, Dog, Cow, Pig |
| Specifications |
| FITC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1 |
| Polyclonal |
| #REF! |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 50848 |
| Q9Y624 |
| Cell membrane |
| JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; F11R; UNQ264/PRO301 |
| Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
| Application Dilution |
| WB |
1:300-5000 |