AMPK alpha-1 (Thr198) Antibody, ALEXA FLUOR® 350 Conjugated

Applications

WB
FCM
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human
Mouse
Rat
Dog

Predicted Reactivity

Cow
Sheep
Pig
Horse
Chicken
Rabbit

Overview
Catalog #	bs-5551R-A350
Product Name	AMPK alpha-1 (Thr198) Antibody, ALEXA FLUOR® 350 Conjugated
Applications	WB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human, Mouse, Rat, Dog
Predicted Reactivity	Cow, Sheep, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation	ALEXA FLUOR® 350
Host	Rabbit
Source	KLH conjugated synthetic phosphopeptide derived from human PRKAA1 around the phosphorylation site of Thr198
Modification Site	Thr198
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	5562
Subcellular location	Cytoplasm, Nucleus
Synonyms	AMPK alpha 1 + AMPK alpha 2 phospho S485 + S491; PRKAA1phospho S79; 5 AMP activated protein kinase alpha 1catalytic subunit; 5 AMP activated protein kinase catalytic alpha 1 chain; 5' AMP activated protein kinase catalytic subunit alpha 1; AAPK1;acetyl CoA carboxylase kinase;AI194361 antibody AI450832 ;AL024255 ;AMP -activate kinase alpha 1 subunit;AMP-activated protein kinase, catalytic, alpha -1;AMPK 1;AMPK alpha 1 chain;AMPK antibody AMPK1; AMPKa1;AMPKalpha1;C130083N04Rik;cb116 antibody EC 2.7.11.1; HMG CoA reductase kinase;hormone sensitive lipase kinase;im:7154392 antibody kinase AMPK alpha1 ;MGC33776;MGC57364 antibody PRKAA 1;PRKAA1;Protein kinase AMP activated alpha 1 catalytic subunit; SNF1-like protein AMPK;wu:fa94C10.
Background	The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].
Application Dilution
WB	1:300-5000
FCM	1:20-100
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200

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