| Overview |
| bs-0920R-A594 |
| VCAM1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated |
| WB, IF(IHC-P), IF(ICC) |
| Human, Mouse, Rat, Sheep, Rabbit |
| Pig |
| Specifications |
| ALEXA FLUOR® 594 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human VCAM-1 |
| 651-739/739 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 7412 |
| P19320 |
| Cell membrane |
| CD106; INCAM-1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; VCAM1; L1CAM |
| Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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