Fibrinopeptide A Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated

Applications

IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human

Overview
Catalog #	bs-10080R-A750
Product Name	Fibrinopeptide A Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated
Applications	IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human
Specifications
Conjugation	ALEXA FLUOR® 750
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human Fibrinopeptide A
Immunogen Range	20-120/866
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	2243
Swiss Prot	P02671
Subcellular location	Secreted
Synonyms	FGA; Fib2; FIBA_HUMAN; Fibrinogen alpha chain; fibrinogen alpha chain isoform alpha preproprotein; Fibrinogen alpha/alpha E chain [Precursor]; fibrinogen alpha chain isoform alpha-E preproprotein; fibrinogen alpha chain isoform alpha preproprotein.
Background	The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
Application Dilution
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200

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