| Overview |
| bs-13004R-A350 |
| Dishevelled 2 (Ser143) Antibody, ALEXA FLUOR® 350 Conjugated |
| WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Zebrafish |
| Mouse, Rat |
| Specifications |
| ALEXA FLUOR® 350 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human Dishevelled 2 around the phosphorylation site of Ser143 |
| Ser143 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1856 |
| Cytoplasm, Cell membrane |
| Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2; DVL2 |
| Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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