| Overview |
| bs-19199R-Cy3 |
| Nephrin (Tyr1217) Polyclonal Antibody, Cy3 Conjugated |
| WB |
| This phosphorylation site is homologous to that of Tyr1232 in Mouse and Tyr1228 Rat. |
| Human |
| Mouse, Rat |
| Specifications |
| Cy3 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human Nephrin around the phosphorylation site of Tyr1217. |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4868 |
| O60500 |
| Cell membrane |
| CNF; NPHN; nephrin; Renal glomerulus-specific cell adhesion receptor; NPHS1 |
| Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
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